Correlation of biochemical parameters and neonatal outcome in patients with gestational hypertension

Clin Exp Hypertens. 2013;35(1):6-10. doi: 10.3109/10641963.2012.685533. Epub 2012 May 22.

Abstract

Hypertensive disorders in pregnancy are one of the leading causes of maternal death in the world and one of the major causes of perinatal mortality. The incidence of hypertensive disorders in pregnancy is 8%-15%. Significant changes of biochemical parameters in cases of hypertensive disorders in pregnancy are increased levels of blood glucose, urea, creatinine, uric acid (hyperuricemia), transaminases, and LDH. The most increased is the level of proteinuria. Bad laboratory results and the intensification of clinical signs, with multiorgan dysfunction, are indications for termination of pregnancy.

MeSH terms

  • Apgar Score
  • Blood Glucose / metabolism
  • Case-Control Studies
  • Creatinine / blood
  • Female
  • HELLP Syndrome / etiology
  • HELLP Syndrome / metabolism
  • Humans
  • Hypertension, Pregnancy-Induced / blood
  • Hypertension, Pregnancy-Induced / metabolism*
  • Hypertension, Pregnancy-Induced / urine
  • Hyperuricemia / etiology
  • Infant, Newborn
  • L-Lactate Dehydrogenase / blood
  • Male
  • Pre-Eclampsia / etiology
  • Pre-Eclampsia / metabolism
  • Pregnancy
  • Pregnancy Outcome
  • Proteinuria / etiology
  • Urea / blood
  • Uric Acid / blood

Substances

  • Blood Glucose
  • Uric Acid
  • Urea
  • Creatinine
  • L-Lactate Dehydrogenase