Spontaneous clearance of chronic hepatitis C infection in a patient with a 20-year-old HIV-hepatitis C co-infection and chronic active hepatitis

Int J STD AIDS. 2012 Mar;23(3):e48-50. doi: 10.1258/ijsa.2009.009333.

Abstract

We report a case of spontaneous clearance of hepatitis C virus (HCV) in a patient co-infected for 20 years with HCV and HIV, and with an chronic active hepatitis C never treated with anti-HCV regimens. We review the literature of eight anecdotal reports describing the spontaneous resolution of chronic HCV infection among HIV-infected patients, and discuss the virological, immunological, pathogenetic and therapeutic implications of this observation.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Coinfection / diagnosis
  • Coinfection / immunology
  • Coinfection / pathology
  • Coinfection / virology
  • HIV Infections / diagnosis*
  • HIV Infections / immunology
  • HIV Infections / pathology*
  • HIV Infections / virology
  • Hepacivirus / isolation & purification*
  • Hepatitis C, Chronic / diagnosis*
  • Hepatitis C, Chronic / immunology
  • Hepatitis C, Chronic / pathology*
  • Hepatitis C, Chronic / virology
  • Hepatitis, Chronic / diagnosis*
  • Hepatitis, Chronic / immunology
  • Hepatitis, Chronic / pathology*
  • Hepatitis, Chronic / virology
  • Humans
  • Male
  • Middle Aged
  • Viral Load