Two new cyanogenic glucosides from the leaves of Hydrangea macrophylla

Molecules. 2012 May 8;17(5):5396-403. doi: 10.3390/molecules17055396.

Abstract

Chemical investigation of the ethanol extract of the aerial parts of Hydrangea macrophylla collected in the Sichuan Province of China resulted in the isolation of two new cyanogenic glucosides. Their structures were elucidated as [(2R)-2-β-D-glucopyranosyloxy)-2-(3,4-dimethoxy-phenyl)] acetonitrile (1) and {(2R)-2-[α-D-glucopyranosyl(1-->6)β-D-glucopyranosyloxy]-2-(3-hydroxy-4-methoxy-phenyl)}acetonitrile (2) on the basis of extensive spectroscopic analysis (1D, 2D NMR and HRESIMS) and chemical studies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Glucosides / isolation & purification*
  • Glycosides / isolation & purification*
  • Hydrangea / chemistry*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plant Components, Aerial / chemistry*
  • Plant Leaves / chemistry*

Substances

  • Glucosides
  • Glycosides
  • cyanogenic glycosides