Doing meta-analysis in research: a systematic approach

Indian J Dermatol Venereol Leprol. 2012 May-Jun;78(3):242-50. doi: 10.4103/0378-6323.95438.

Abstract

Meta-analysis is an objective, systematic review that employs statistical methods to combine and summarize the results of several studies. It is a quantitative synthesis of all the unbiased evidence, meant for summarizing large volume of data, establishing and determining the magnitude of an effect, and to increase power and precision of studies. The steps to performing a meta-analysis include making a hypothesis and defining the domain of research, defining inclusion/exclusion criteria, literature search, selecting the final set of studies, extracting data on variables of interest, coding procedures, calculating effect sizes and interpretations, selecting potential moderators and examine their relationships, report writing, and critical evaluation. Meta-analysis has several strengths as well as weaknesses.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Biomedical Research / methods*
  • Biomedical Research / standards*
  • Dermatology*
  • Humans
  • Meta-Analysis as Topic*