Sudden infant death in an 8-month-old baby with dengue virus infection: searching for virus in postmortem tissues by immunohistochemistry and Western blotting

Pediatr Infect Dis J. 2012 Aug;31(8):878-80. doi: 10.1097/INF.0b013e31825c4a08.

Abstract

Sudden infant death due to dengue virus infection is very rare. An 8-month-old male infant was found unresponsive during a nap in his nursery school. We emphasize the usefulness of dengue viral antigens as a postmortem diagnostic technique to demonstrate the presence of virus in human tissue specimens by immunohistochemistry and Western blotting.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Viral / blood
  • Antigens, CD
  • Antigens, Viral / isolation & purification
  • Autopsy
  • Blotting, Western
  • Dengue / diagnosis
  • Dengue / immunology
  • Dengue / virology*
  • Dengue Virus / immunology
  • Dengue Virus / isolation & purification*
  • Fatal Outcome
  • Humans
  • Immunohistochemistry
  • Infant
  • Male
  • Sudden Infant Death*

Substances

  • Antibodies, Viral
  • Antigens, CD
  • Antigens, Viral