Pushing the limit: synthesis, photophysical and DNA binding studies of a NIR-emitting Ru(II)-polypyridyl probe with 'light switch' behaviour

Dalton Trans. 2012 Jun 14;41(22):6607-10. doi: 10.1039/c2dt00020b. Epub 2012 May 3.

Abstract

The new Ru(II) polypyridyl complex 1 was synthesised using microwave irradiation from the new polypyridyl ligand 2'DipyTAP', and its photophysical properties, and DNA binding abilities were investigated using various spectroscopic techniques; and 1 was shown to act as a 'NIR molecular light switch' for DNA with an emission window between 680 and 860 nm.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chemistry Techniques, Synthetic
  • DNA / chemistry*
  • DNA / metabolism
  • Light*
  • Models, Molecular
  • Molecular Conformation
  • Organometallic Compounds / chemical synthesis*
  • Organometallic Compounds / chemistry*
  • Organometallic Compounds / metabolism
  • Pyridines / chemistry*
  • Pyridines / metabolism
  • Ruthenium / chemistry*
  • Ruthenium / metabolism
  • Spectrophotometry, Infrared

Substances

  • Organometallic Compounds
  • Pyridines
  • Ruthenium
  • DNA