Maternal superobesity and perinatal outcomes

Am J Obstet Gynecol. 2012 May;206(5):417.e1-6. doi: 10.1016/j.ajog.2012.02.037. Epub 2012 Mar 7.

Abstract

Objective: The purpose of this study was to determine the effect of maternal superobesity (body mass index [BMI], ≥ 50 kg/m(2)) compared with morbid obesity (BMI, 40-49.9 kg/m(2)) or obesity (BMI, 30-39.9 kg/m(2)) on perinatal outcomes.

Study design: We conducted a retrospective cohort study of birth records that were linked to hospital discharge data for all liveborn singleton term infants who were born to obese Missouri residents from 2000-2006. We excluded major congenital anomalies and women with diabetes mellitus or chronic hypertension.

Results: There were 64,272 births that met the study criteria, which included 1185 superobese mothers (1.8%). Superobese women were significantly more likely than obese women to have preeclampsia (adjusted relative risk [aRR], 1.7; 95% confidence interval [CI], 1.4-2.1), macrosomia (aRR, 1.8; 95% CI, 1.3-2.5), and cesarean delivery (aRR, 1.8; 95% CI, 1.5-2.1). Almost one-half of all superobese women (49.1%) delivered by cesarean section, and 33.8% of superobese nulliparous women underwent scheduled primary cesarean delivery.

Conclusion: Women with a BMI of ≥ 50 kg/m(2) are at significantly increased risk for perinatal complications compared with obese women with a lower BMI.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Apgar Score
  • Cesarean Section / statistics & numerical data
  • Cohort Studies
  • Female
  • Fetal Macrosomia / etiology
  • Humans
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Infant, Newborn, Diseases / etiology
  • Length of Stay / statistics & numerical data
  • Logistic Models
  • Male
  • Multivariate Analysis
  • Obesity*
  • Obesity, Morbid
  • Pre-Eclampsia / etiology
  • Pregnancy
  • Pregnancy Complications* / etiology
  • Pregnancy Outcome*
  • Retrospective Studies
  • Risk