Regional changes in coaptation geometry after reduction annuloplasty for functional mitral regurgitation

Ann Thorac Surg. 2012 Jun;93(6):1876-80. doi: 10.1016/j.athoracsur.2012.02.066. Epub 2012 Apr 26.

Abstract

Background: While it is known that band annuloplasty for functional mitral regurgitation (FMR) improves leaflet coaptation, the effect on regional coaptation geometry has not previously been well defined. We used three-dimensional transesophageal echocardiography (3D-TEE) to analyze the regional effects of semirigid band annuloplasty on annular geometry and leaflet coaptation zones of patients with FMR.

Methods: Sixteen patients with severe FMR underwent a semirigid band annuloplasty. Intraoperative full volume 3D-TEE datasets were acquired pre valve and post valve repair. Offline analysis assessed annular dimensions and regional coaptation zone geometry. The regions were defined as R1 (A1-P1), R2 (A2-P2), and R3 (A3-P3); coaptation distance, coaptation depth, and coaptation length were measured in each region. Differences were analyzed with repeated measures within a general linear model.

Results: Band annuloplasty decreased mitral regurgitation grade from 3.7 to 0.1 (scale 0 to 4). Annular septolateral dimension (p<0.01) and coaptation distance (p<0.01) decreased significantly in all regions. Likewise, anterior and posterior leaflet coaptation lengths increased in all regions (p<0.01 and p=0.05, respectively), with region 2 showing the greatest increase (p=0.01). Changes in coaptation depth were not significant.

Conclusions: Semirigid band annuloplasty for FMR produces significant regional remodeling of leaflet coaptation zones, with region 2 showing the greatest increase in leaflet coaptation length. This regional analysis of annular geometry and leaflet coaptation creates a framework to better understand the mechanisms of surgical success or failure of annuloplasty for FMR.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cardiac Valve Annuloplasty / instrumentation
  • Cardiac Valve Annuloplasty / methods*
  • Echocardiography, Three-Dimensional*
  • Echocardiography, Transesophageal*
  • Female
  • Humans
  • Linear Models
  • Male
  • Middle Aged
  • Mitral Valve Insufficiency / diagnostic imaging*
  • Mitral Valve Insufficiency / surgery*
  • Outcome Assessment, Health Care
  • Postoperative Complications / diagnostic imaging*