Cerebro-rhino orbital mucormycosis: an update

J Infect Public Health. 2012 Apr;5(2):116-26. doi: 10.1016/j.jiph.2012.01.003. Epub 2012 Mar 27.

Abstract

Mucormycosis is an uncommon fungal infection which can lead to fulminant necrotizing infection under optimal host condition. Fungi have the ability to invade blood vessels and can affect different parts of the body. The most common, though the most aggressive, form is cerebro-rhino-orbital mucormycosis that occurs in debilitated patients, in conjunction with sinus or para-sinus involvement. Due to increased number of newly diagnosed cases of mucormycosis world-wide resulting from uncontrolled metabolic conditions, this paper intends to widen the reader's scope and knowledge about the nature of the disease and its multicomplexity that require a collaborative effort for careful management. Patients who are at risks both at the onset of the disease and during its management have been identified in the paper.

Publication types

  • Review

MeSH terms

  • Central Nervous System Fungal Infections / complications*
  • Central Nervous System Fungal Infections / diagnosis
  • Central Nervous System Fungal Infections / microbiology*
  • Central Nervous System Fungal Infections / therapy
  • Humans
  • Mucormycosis / diagnosis
  • Mucormycosis / epidemiology
  • Mucormycosis / microbiology*
  • Mucormycosis / therapy
  • Orbital Diseases / complications*
  • Orbital Diseases / diagnosis
  • Orbital Diseases / microbiology*
  • Orbital Diseases / therapy
  • Rhinitis / complications*
  • Rhinitis / diagnosis
  • Rhinitis / microbiology*
  • Rhinitis / therapy