An assessment of different scoring systems in cirrhotic patients undergoing nontransplant surgery

Am J Surg. 2012 May;203(5):589-593. doi: 10.1016/j.amjsurg.2012.01.009.

Abstract

Background: Determining surgical risk in cirrhotic patients is difficult and multiple scoring systems have sought to quantify this risk. The purpose of our study was to assess the impact of Childs-Turcotte-Pugh (CTP), Model of End-Stage Liver Disease (MELD), and MELD-Sodium (MELD-Na) scores on postoperative morbidity and mortality for cirrhotic patients undergoing nontransplant surgery.

Methods: We performed a single-center retrospective review of all cirrhotic patients who underwent nontransplant surgery under general anesthesia over a 6-year period of time to analyze outcomes using the 3 scoring systems.

Results: Sixty-four cirrhotic patients (mean age, 57 y; 62 men) underwent nontransplant surgery under general anesthesia. A CTP score of ≥ 7.5 was associated with an 8.3-fold increased risk of 30-day morbidity, a MELD score of ≥ 14.5 was associated with a 5.4-fold increased risk of 3-month mortality, and a MELD-Na score ≥ 14.5 was associated with a 4.5-fold increased risk of 1-year mortality. Emergent surgery, the presence of ascites, and low serum sodium level were associated significantly with morbidity and 1-year mortality.

Conclusions: The major strengths of the 3 scoring systems are for CTP in estimating 30-day morbidity, MELD for estimating 3-month mortality, and MELD-Na for estimating 1-year mortality.

MeSH terms

  • End Stage Liver Disease
  • Female
  • Humans
  • Liver Cirrhosis / surgery*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Assessment
  • Severity of Illness Index