Mycophenolate mofetil use in the treatment of noninfectious uveitis

Dev Ophthalmol. 2012:51:57-62. doi: 10.1159/000336192. Epub 2012 Apr 17.

Abstract

Mycophenolate mophetil (MMP) is a potent immunomodulatory drug that inhibits the function of T and B lymphocytes. It is used successfully in the treatment of recurrent noninfectious uveitis in adults and children. MMF can be used alone or in combination with other immunomodulatory drugs (biologics or calcineurin inhibitors) for moderate and severe cases of anterior, intermediate and posterior uveitis. It can also be used for treatment of patients with scleritis and ocular cicatricial pemphigoid.

Publication types

  • Review

MeSH terms

  • Humans
  • Immunity, Cellular / drug effects
  • Immunosuppressive Agents / therapeutic use*
  • Mycophenolic Acid / analogs & derivatives*
  • Mycophenolic Acid / therapeutic use
  • Prodrugs
  • Treatment Outcome
  • Uveitis / drug therapy*
  • Uveitis / immunology

Substances

  • Immunosuppressive Agents
  • Prodrugs
  • Mycophenolic Acid