Is there an affective working memory deficit in patients with chronic schizophrenia?

Schizophr Res. 2012 Jun;138(1):99-101. doi: 10.1016/j.schres.2012.03.028. Epub 2012 Apr 15.

Abstract

Research interest in affective working memory has rapidly grown in the last decade. In this study we investigated working memory functions for affective and neutral words in a group of 22 patients with chronic schizophrenia and 22 healthy controls. In particular, participants were administered the operation working memory span task in which affective and neutral words had to be remembered. Results showed that patients made significantly more intrusion errors, recalling off-goal information, and showed poorer long-term memory performance than controls. In addition, affective trials showed the largest number of intrusion errors. These results suggest that a general attentional control deficit, especially over affective information, may underly failures to remember in chronic schizophrenia patients.

MeSH terms

  • Adult
  • Affect*
  • Case-Control Studies
  • Female
  • Humans
  • Male
  • Memory Disorders / complications
  • Memory Disorders / physiopathology*
  • Memory, Short-Term*
  • Mental Recall*
  • Middle Aged
  • Neuropsychological Tests
  • Recognition, Psychology*
  • Schizophrenia / complications
  • Schizophrenia / physiopathology*