[Targeted chemotherapy for breast cancer: patients perception of the use of tumor gene profiling approaches to better adapt treatments]

Med Sci (Paris). 2012 Mar:28 Spec No 1:24-7. doi: 10.1051/medsci/2012281s107. Epub 2012 Apr 9.
[Article in French]

Abstract

The purpose of this review of the literature is to document how breast cancer patients perceive the use of tumor gene profiling approaches to better adapt treatments, and to identify the features of these approaches that may impact their clinical application. In general, the use of tumor genomic analysis was perceived by patients as an approach facilitating personalized medicine and received considerable support. Nevertheless, a number of confusions and worries about these practices were also identified. Improving the quality of provider/patient communications should enable patients to play a more active part in the decision-making about their treatment. This will ensure that those who agree to their tumor gene analysis have realistic expectations and sound deductions of the final result disclosure process.

Publication types

  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / genetics
  • Breast Neoplasms / psychology
  • Carcinoma / drug therapy*
  • Carcinoma / genetics
  • Carcinoma / psychology
  • Communication Barriers
  • Female
  • Gene Expression Profiling* / statistics & numerical data
  • Humans
  • Molecular Diagnostic Techniques / methods
  • Molecular Targeted Therapy / statistics & numerical data*
  • Perception / physiology*
  • Precision Medicine / psychology*