Abstract
This meta-analysis of 13 studies revealed that amphotericin B delivered as a locally prepared lipid emulsion or in liposomes reduced nephrotoxicity to a similar degree, by 18.4% (relative risk [RR], 0.40 [99% confidence interval, .25-.64]; n = 459) and 18.1% (RR, 0.48 [99% CI, .36-.64]); n = 1233), respectively.
Publication types
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Meta-Analysis
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Research Support, Non-U.S. Gov't
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Review
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Systematic Review
MeSH terms
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Amphotericin B / administration & dosage*
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Amphotericin B / adverse effects*
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Antifungal Agents / administration & dosage*
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Antifungal Agents / adverse effects*
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Humans
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Incidence
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Kidney Diseases / chemically induced*
Substances
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Antifungal Agents
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liposomal amphotericin B
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Amphotericin B