Abstract
Hydrogen sulfide (H(2)S) is an important biological messenger but few biologically-compatible methods are available for its detection. Here we report two bright fluorescent probes that are selective for H(2)S over cysteine, glutathione and other reactive sulfur, nitrogen, and oxygen species. Both probes are demonstrated to detect H(2)S in live cells.
This journal is © The Royal Society of Chemistry 2012
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Cysteine / chemistry
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Fluorescent Dyes / chemical synthesis
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Fluorescent Dyes / chemistry*
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Glutathione / chemistry
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HeLa Cells
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Humans
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Hydrogen Sulfide / analysis*
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Molecular Structure
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Naphthalimides / chemical synthesis*
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Naphthalimides / chemistry
Substances
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Fluorescent Dyes
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Naphthalimides
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Glutathione
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Cysteine
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Hydrogen Sulfide