Research progress on mechanism of action of Radix Astragalus in the treatment of heart failure

Qing-You Yang; Ke-Ji Chen; Shu Lu; Hui-Ru Sun

doi:10.1007/s11655-012-1022-1

Research progress on mechanism of action of Radix Astragalus in the treatment of heart failure

Chin J Integr Med. 2012 Mar;18(3):235-40. doi: 10.1007/s11655-012-1022-1. Epub 2012 Apr 2.

Authors

Qing-You Yang¹, Ke-Ji Chen, Shu Lu, Hui-Ru Sun

Affiliation

¹ Department of Cardiovascular Diseases, Wuxi Municipal Hospital of Traditional Chinese Medicien, Wuxi City, Jiangsu Province 214001, China.

PMID: 22466951
DOI: 10.1007/s11655-012-1022-1

Abstract

This paper reviewed the retrieved literature published in the last 10 years, regarding the mechanism of Radix Astragalus in treating heart failure, in aspects of myocardial contraction improvement, cardiac muscle cell protection, neuro-endocrinal system regulation, relative cytokine regulation, and left ventricular remodeling inhibition, etc.

Publication types

Review

MeSH terms

Astragalus Plant
Astragalus propinquus
Biomedical Research / trends*
Cytoprotection / drug effects
Drugs, Chinese Herbal / pharmacology
Drugs, Chinese Herbal / therapeutic use*
Heart Failure / drug therapy*
Heart Failure / physiopathology
Heart Failure / prevention & control
Humans
Myocardial Contraction / drug effects
Myocytes, Cardiac / drug effects
Myocytes, Cardiac / pathology

Substances

Drugs, Chinese Herbal
Huang Qi