Effect of ovarian stimulation and oocyte retrieval on reproductive outcome in oocyte donors

Fertil Steril. 2012 Jun;97(6):1328-30. doi: 10.1016/j.fertnstert.2012.03.012. Epub 2012 Mar 30.

Abstract

Objective: To assess whether there is an increased risk of infertility in women that have previously undergone ovarian stimulation and oocyte retrieval for oocyte donation.

Design: Cross-sectional survey.

Setting: Tertiary referral center.

Patient(s): A total of 194 past oocyte donors.

Intervention(s): Telephone questionnaire.

Main outcome measure(s): Incidence of infertility after oocyte donation.

Result(s): Of the women who indicated having pursued conception after oocyte donation, 95% (57/60) became pregnant unassisted. Before oocyte donation, 41 women in this cohort had already been trying to conceive, of which 38 had delivered a child and 3 (7.3%) had needed infertility treatment.

Conclusion(s): The data suggest that oocyte donation does not affect short-term reproductive health.

MeSH terms

  • Adult
  • Carbolines
  • Cohort Studies
  • Cross-Sectional Studies
  • Female
  • Humans
  • Infertility, Female / epidemiology*
  • Oocyte Donation / adverse effects
  • Oocyte Donation / statistics & numerical data*
  • Oocyte Retrieval / adverse effects
  • Oocyte Retrieval / statistics & numerical data*
  • Ovulation Induction / adverse effects
  • Ovulation Induction / statistics & numerical data*
  • Pregnancy
  • Pregnancy Outcome / epidemiology
  • Pregnancy Rate*
  • Risk Factors
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Carbolines
  • diazoline