Anxiolytic activity of tenoten and diazepam depends on conditions in Vogel conflict test
Bull Exp Biol Med. 2011 Jul;151(3):336-9.
doi: 10.1007/s10517-011-1324-x.
[Article in
English,
Russian]
Affiliation
- 1 Materia Medica Holding, Moscow, Russia. nauka@materiamedica.ru
Abstract
We compared two modifications of Vogel conflict test and assessed anxyolitic activity of two drugs: diazepam (benzodiazepine anxiolitic) and tenoten (ultra-low doses of antibodies to S-100 protein) in both modifications of the test. It was found that the intensity of anxiolitic effect of the drugs depends on the conditions of Vogel test.
MeSH terms
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Animals
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Anti-Anxiety Agents / pharmacology*
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Antibodies / pharmacology*
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Anxiety / drug therapy*
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Behavior, Animal / drug effects
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Diazepam / pharmacology*
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Drug Evaluation, Preclinical
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Electroshock
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Male
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Rats
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Water Deprivation
Substances
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Anti-Anxiety Agents
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Antibodies
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tenoten
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Diazepam