Candida esophagitis with fever alone in a patient with stroke

Brain Inj. 2012;26(6):896-8. doi: 10.3109/02699052.2012.666371. Epub 2012 Mar 26.

Abstract

Background: Candida esophagitis is a rare disease, but its incidence is higher in patients with impaired immunity due to an underlying disease. Patients with candida esophagitis usually present with lower retrosternal pain or dysphagia, but they are sometimes asymptomatic. Several risk factors, including diabetes mellitus, malignancies, chronic obstructive pulmonary disease (COPD) and steroid therapy, have been shown to be associated with candida esophagitis. Candida esophagitis may mimic other disease processes and can thus be misdiagnosed.

Case study: This study describes a case of candida esophagitis with fever alone in the patient with stroke. After a stroke attack, a 53-year-old man was hospitalized for rehabilitation. He had a fever unexpectedly, but the cause could not be found for 2 weeks. Esophagogastroduodenoscopy (EGD) was performed to find the cause of the fever and it was diagnosed as candida eosphagitis. Fever decreased respectively 4 days after anti-fungal therapy begun.

Conclusion: Dysphagia, unexplained anaemia, loss of appetite and dyspepsia may require EGD to make a confirmative diagnosis. If unexplained fever is persistent without any of these symptoms, it is advisable to consider EGD in patients with stroke.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / therapeutic use
  • Candidiasis / complications
  • Candidiasis / diagnosis*
  • Candidiasis / drug therapy
  • Esophagitis / etiology
  • Esophagitis / microbiology*
  • Fever / etiology
  • Fever / microbiology*
  • Humans
  • Male
  • Middle Aged
  • Risk Factors
  • Stroke / complications*
  • Treatment Outcome

Substances

  • Antifungal Agents