Low-frequency electrotherapy for female patients with detrusor underactivity due to neuromuscular deficiency

Int Urogynecol J. 2012 Aug;23(8):1007-15. doi: 10.1007/s00192-012-1714-2. Epub 2012 Mar 23.

Abstract

Introduction and hypothesis: The aim of the study was to assess the efficacy of low-frequency electrotherapy (LFE) for female patients with early-stage detrusor underactivity (DUA) due to neuromuscular deficiency.

Methods: A total of 102 female patients were divided randomly into four groups: LFE-NC (normal compliance), LFE-LC (low compliance), CON (control)-NC and CON-LC. Patients in the LFE-NC and LFE-LC groups received LFE, and those in the CON-NC and CON-LC groups received conservative treatment. Urodynamic evaluation was performed before and after treatment.

Results: After treatment, 82 % of the LFE-NC regained detrusor contractility, whereas only 2 (8 %) of the CON-NC had normal detrusor contraction. None of LFE-LC or CON-LC regained detrusor contractility (p < 0.01). The per cent of LFE-NC who relied on catheterization for bladder emptying decreased by 43 % (p < 0.01). Those in the LFE-LC, CON-NC and CON-LC groups decreased by only 4, 12 or 0 % (p > 0.05).

Conclusions: LFE was more effective for DUA patients with normal compliance; these patients benefited from LFE, but DUA patients with low compliance did not.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Electric Stimulation Therapy / methods*
  • Female
  • Humans
  • Middle Aged
  • Neuromuscular Diseases / complications*
  • Neuromuscular Diseases / physiopathology
  • Patient Compliance
  • Treatment Outcome
  • Urinary Bladder / physiopathology*
  • Urinary Bladder Diseases / etiology*
  • Urinary Bladder Diseases / physiopathology
  • Urodynamics / physiology