Bismuth ferrite clusters induced hydrogel formation in human serum albumin

Garima Thakur; Prashanthi Kovur; Roger M Leblanc; Thomas Thundat

doi:10.1039/c2cc30525a

Bismuth ferrite clusters induced hydrogel formation in human serum albumin

Chem Commun (Camb). 2012 May 4;48(35):4193-5. doi: 10.1039/c2cc30525a. Epub 2012 Mar 23.

Authors

Garima Thakur¹, Prashanthi Kovur, Roger M Leblanc, Thomas Thundat

Affiliation

¹ Department of Chemical and Material Engineering, University of Alberta, Edmonton, Canada. garima.thakur@ualberta.ca

PMID: 22441202
DOI: 10.1039/c2cc30525a

Abstract

Amyloid-fibril formation in human serum albumin (HSA) led to hydrogel formation in the presence of clusters of bismuth ferrite (BiFeO(3) or BFO) nanoparticles (NPs). Factors responsible for hydrogel formation were size and phase of NPs.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bismuth / chemistry*
Circular Dichroism
Ferric Compounds / chemistry*
Humans
Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry*
Metal Nanoparticles / chemistry*
Serum Albumin / chemistry*
Serum Albumin / metabolism

Substances

Ferric Compounds
Serum Albumin
Hydrogel, Polyethylene Glycol Dimethacrylate
Bismuth