A case of canine chimerism diagnosed using coat color tests

Dayna L Dreger; Sheila M Schmutz

doi:10.1016/j.mcp.2012.03.004

A case of canine chimerism diagnosed using coat color tests

Mol Cell Probes. 2012 Dec;26(6):253-5. doi: 10.1016/j.mcp.2012.03.004. Epub 2012 Mar 13.

Authors

Dayna L Dreger¹, Sheila M Schmutz

Affiliation

¹ Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, 51 Campus Drive, Saskatoon, SK, Canada S7N 5A8. DLD842@mail.usask.ca

PMID: 22433982
DOI: 10.1016/j.mcp.2012.03.004

Abstract

Through the use of PCR based coat color tests, we were able to diagnose a dog that exhibits an unusual coat color phenotype as an XX/XX chimera. Coat color alleles vary widely among dog breeds, presenting a novel method for detecting chimerism using diagnostic tests for known coat color alleles.

MeSH terms

Agouti Signaling Protein / genetics
Amplified Fragment Length Polymorphism Analysis
Animals
Chimera / genetics*
Dogs / genetics*
Female
Hair Color / genetics*
Molecular Diagnostic Techniques
Receptor, Melanocortin, Type 1 / genetics
Sex Determination Analysis

Substances

Agouti Signaling Protein
Receptor, Melanocortin, Type 1
a protein, mouse