Abstract
β-ketoesters are robust probes for labeling sulfenic acid (-SOH) proteins allowing quantitative cleavage of the tag for improved analysis of the labeled peptides by MS.
This journal is © The Royal Society of Chemistry 2012
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Animals
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Cell Survival
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Cysteine / analogs & derivatives*
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Cysteine / analysis
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Esters / chemistry
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Ketones / chemistry
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Mice
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Models, Molecular
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NIH 3T3 Cells
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Proteins / chemistry*
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Spectrometry, Mass, Electrospray Ionization*
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Staining and Labeling
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Sulfenic Acids / analysis*
Substances
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Esters
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Ketones
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Proteins
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Sulfenic Acids
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cysteinesulfenic acid
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Cysteine