Regiodivergent synthesis of functionalized indene derivatives via Pt-catalyzed Rautenstrauch reaction of propargyl carbonates

Jinbo Zhao; Daniel A Clark

doi:10.1021/ol300158d

Regiodivergent synthesis of functionalized indene derivatives via Pt-catalyzed Rautenstrauch reaction of propargyl carbonates

Org Lett. 2012 Apr 6;14(7):1668-71. doi: 10.1021/ol300158d. Epub 2012 Mar 14.

Authors

Jinbo Zhao¹, Daniel A Clark

Affiliation

¹ 1-014 Center for Science and Technology, Department of Chemistry, Syracuse University, Syracuse, New York 13244, USA.

PMID: 22416889
DOI: 10.1021/ol300158d

Abstract

A regiodivergent synthesis of functionalized indene derivatives from a Pt-catalyzed Rautenstrauch reaction of propargyl carbonate is described. A one-pot Rautenstrauch/Tsuji-Trost reaction delivering 2-indanones was realized efficiently using this methodology.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkynes / chemistry*
Carbonates / chemistry*
Catalysis
Cyclization
Indenes / chemical synthesis*
Indenes / chemistry
Molecular Structure
Platinum / chemistry*
Stereoisomerism

Substances

Alkynes
Carbonates
Indenes
Platinum