Abstract
We report a genetically encoded fluorescent sensor for in vivo copper(I) imaging based on engineered intramolecular mechanical strain and structural distortion of EGFP.
This journal is © The Royal Society of Chemistry 2012
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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CHO Cells
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Copper / analysis*
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Cricetinae
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Cricetulus
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Green Fluorescent Proteins / chemistry*
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Green Fluorescent Proteins / genetics
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Green Fluorescent Proteins / metabolism
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Microscopy, Fluorescence
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Spectrometry, Fluorescence*
Substances
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enhanced green fluorescent protein
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Green Fluorescent Proteins
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Copper