Chemical constituents of the aerial part of Derris elliptica

Xinzhou Wu; Zhijun Song; Hanhong Xu; Heng Zhang; Weiquan Chen; Huaying Liu

doi:10.1016/j.fitote.2012.02.015

Chemical constituents of the aerial part of Derris elliptica

Fitoterapia. 2012 Jun;83(4):732-6. doi: 10.1016/j.fitote.2012.02.015. Epub 2012 Mar 5.

Authors

Xinzhou Wu¹, Zhijun Song, Hanhong Xu, Heng Zhang, Weiquan Chen, Huaying Liu

Affiliation

¹ Key Laboratory of Natural Pesticide and Chemical Biology, Ministry of Education, South China Agricultural University, Guangzhou 510642, People's Republic of China.

PMID: 22414317
DOI: 10.1016/j.fitote.2012.02.015

Abstract

A new coumaronochromone, 6,4'-dihydroxy-7,5' -dimethoxy-coumaronochromone (1), together with eleven known flavonoids (2-12) were isolated from the ethanol extract of the aerial part of Derris elliptica. Their structures were elucidated on the basis of spectroscopic analysis. Compounds 2, 4, 7, 8 and 9 exhibited moderate insecticidal activities against larvae of Aedes albopictus. All compounds showed strong cytotoxic activities against Spodoptera litura (SL) and Trichoplusia ni BTI-Tn-5B1-4 (Hi-5) cells comparison to positive control of rotenone.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aedes / drug effects*
Animals
Benzofurans / chemistry
Benzofurans / isolation & purification*
Benzofurans / pharmacology
Cell Line
Chromones / chemistry
Chromones / isolation & purification*
Chromones / pharmacology
Derris / chemistry*
Flavonoids / chemistry
Flavonoids / isolation & purification*
Flavonoids / pharmacology
Insecticides / chemistry
Insecticides / isolation & purification*
Insecticides / pharmacology
Larva / drug effects
Molecular Structure
Moths / drug effects*
Plant Components, Aerial / chemistry*
Plant Extracts / chemistry
Plant Extracts / pharmacology
Rotenone / pharmacology

Substances

6,4'-dihydroxy-7,5'-dimethoxy-coumaronochromone
Benzofurans
Chromones
Flavonoids
Insecticides
Plant Extracts
Rotenone