Is local ointment or cauterization more effective in childhood recurrent epistaxis

Int J Pediatr Otorhinolaryngol. 2012 Jun;76(6):783-6. doi: 10.1016/j.ijporl.2012.02.040. Epub 2012 Mar 10.

Abstract

Objectives: To compare the efficacy of nasal antiseptic ointment and silver nitrate cautery in the treatment of children with recurrent epistaxis.

Methods: In this prospective and randomized study, a hundred children with recurrent epistaxis were assigned into two groups. In group 1, patients underwent silver nitrate cauterization, in group 2 patients were treated with nasal antiseptic ointment (oxytetracycline hydrochloride-polymyxin B sulfate); and both groups were followed for 3 months. All of the patients were investigated for allergy with skin prick test.

Results: The ages of patients were similar in both groups (group 1: 9.2±2.7; group 2: 8.2±2.2; p=0.069). Thirty-eight percent of the patients in group 1 and 52% of the patients in group 2 had epistaxis in the three months follow-up. The difference between groups was not significant (p=0.159). Thirteen (26%) of the patients in group 1 and 12 (24%) of the patients in group 2 were found to have allergic symptoms and positive prick test. The rate of allergy was similar in both groups (p=0.817).

Conclusion: Nasal antiseptic ointment and silver nitrate cauterization were found to have similar outcomes in the treatment of recurrent epistaxis.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Administration, Intranasal
  • Adolescent
  • Anti-Infective Agents, Local / therapeutic use*
  • Cautery / methods*
  • Child
  • Child, Preschool
  • Epistaxis / diagnosis
  • Epistaxis / drug therapy*
  • Epistaxis / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Ointments / therapeutic use
  • Prospective Studies
  • Recurrence
  • Risk Assessment
  • Severity of Illness Index
  • Silver Nitrate*
  • Treatment Outcome

Substances

  • Anti-Infective Agents, Local
  • Ointments
  • Silver Nitrate