Seroprevalence of hepatitis E virus infection in rural and urban populations, Tunisia

Clin Microbiol Infect. 2012 May;18(5):E119-21. doi: 10.1111/j.1469-0691.2012.03793.x. Epub 2012 Mar 9.

Abstract

Hepatitis E virus (HEV) is one of the leading agents of acute hepatitis. This study investigated the prevalence and risk factors of HEV infection in the Tunisian adult general population, either in blood donors (n=687) or in patients hospitalized for acute hepatitis (n=202). The mode of transmission differed between these two populations: contact with animals and living in a rural habitat were the main risk factors for being in contact with HEV in asymptomatic blood donors, while HEV was contracted through contaminated water in symptomatic cases. HEV seroprevalence in adult blood donors in Tunisia was relatively low (5.4%) and increased with age.

MeSH terms

  • Adult
  • Animals
  • Antibodies, Viral / blood
  • Blood Donors
  • Female
  • Hepatitis Antibodies / blood*
  • Hepatitis E / epidemiology*
  • Hepatitis E / virology
  • Hepatitis E virus / immunology*
  • Humans
  • Immunoglobulin G / blood
  • Male
  • Middle Aged
  • Risk Factors
  • Rural Population / statistics & numerical data*
  • Seroepidemiologic Studies
  • Tunisia / epidemiology
  • Urban Population / statistics & numerical data*
  • Young Adult
  • Zoonoses / epidemiology
  • Zoonoses / virology

Substances

  • Antibodies, Viral
  • Hepatitis Antibodies
  • Immunoglobulin G