Update of spectroscopic data for 4-hydroxydictyolactone and dictyol E isolated from a Halimeda stuposa - Dictyota sp. assemblage

Molecules. 2012 Mar 8;17(3):2929-38. doi: 10.3390/molecules17032929.

Abstract

The methanol extract of an assemblage of Halimeda stuposa and a Dictyota sp., yielded three natural products characteristic of Dictyota sp., and one of Halimeda sp. These included the xenicane diterpene 4-hydroxydictyolactone (1), and the diterpenes dictyol E (2), 8a,11-dihydroxypachydictyol A (3) and indole-3-carboxaldehyde (4). A minor revision of 1 and new spectroscopic data for 1 and 2 are provided, along with associated anti-cancer activities of compounds.

MeSH terms

  • Animals
  • Antineoplastic Agents / chemistry*
  • Antineoplastic Agents / isolation & purification
  • Antineoplastic Agents / pharmacology
  • CHO Cells
  • Cell Line, Tumor
  • Chlorophyta / chemistry*
  • Cricetinae
  • Diterpenes / chemistry*
  • Diterpenes / isolation & purification
  • Diterpenes / pharmacology
  • Drug Screening Assays, Antitumor
  • Euryarchaeota / chemistry
  • Humans
  • Indoles / chemistry
  • Indoles / isolation & purification
  • Indoles / pharmacology
  • Magnetic Resonance Spectroscopy
  • Molecular Conformation
  • Plant Extracts / chemistry*
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology
  • Solvents / chemistry

Substances

  • 4-hydroxydictyolactone
  • 8alpha,11-dihydroxypachydictyol A
  • Antineoplastic Agents
  • Diterpenes
  • Indoles
  • Plant Extracts
  • Solvents
  • dictyol E
  • indole-3-carbaldehyde