Unusual regression of severe recurrent lymphatic malformation of a face after contraception and pregnancy

Gynecol Endocrinol. 2012 Oct;28(10):764-6. doi: 10.3109/09513590.2012.664190. Epub 2012 Mar 9.

Abstract

We report the case of a female who had suffered from progressive lymphatic malformation in the orbito-temporal region since childhood. Many surgical interventions were performed, including radical excision and shunt drainage. Despite aggressive surgical treatment, recurrence was observed after every intervention. Eventually, the condition regressed after the patient began taking a contraceptive. Moreover, it virtually disappeared after pregnancy.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Contraceptives, Oral, Combined / administration & dosage*
  • Contraceptives, Oral, Combined / therapeutic use
  • Drug Combinations
  • Ethinyl Estradiol / administration & dosage*
  • Ethinyl Estradiol / therapeutic use
  • Facial Neoplasms / complications
  • Facial Neoplasms / surgery
  • Facial Neoplasms / therapy
  • Female
  • Humans
  • Lymphangioma / complications
  • Lymphangioma / surgery
  • Lymphangioma / therapy
  • Lymphatic Abnormalities / complications
  • Lymphatic Abnormalities / physiopathology*
  • Lymphatic Abnormalities / surgery
  • Lymphatic Abnormalities / therapy*
  • Norgestrel / administration & dosage
  • Norgestrel / analogs & derivatives*
  • Norgestrel / therapeutic use
  • Orbit
  • Postoperative Complications / prevention & control
  • Pregnancy
  • Pregnancy Complications / prevention & control
  • Recurrence
  • Remission Induction
  • Temporal Bone
  • Young Adult

Substances

  • Contraceptives, Oral, Combined
  • Drug Combinations
  • norgestimate, ethinyl estradiol drug combination
  • Norgestrel
  • Ethinyl Estradiol