"My parents died of myocardial infarction: is that my destiny?"

Med Clin North Am. 2012 Jan;96(1):67-86. doi: 10.1016/j.mcna.2011.11.001.

Abstract

This article presents an overview of clinical and molecular genetics of myocardial infarction (MI). Discussion includes the partial overlapping of risk factors for myocardial infarction and atherosclerosis, the impact of a positive family history on the risk of MI, the "familial" nongenetic, environmental factors, the inherited risk associated with the low-dose input of many genes, and a simple approach to stratify the individual risk in genetic counseling.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Atherosclerosis* / epidemiology
  • Atherosclerosis* / genetics
  • Atherosclerosis* / psychology
  • Effect Modifier, Epidemiologic
  • Family Health
  • Gene-Environment Interaction
  • Genetic Counseling
  • Genetic Predisposition to Disease*
  • Genome-Wide Association Study
  • Humans
  • Multifactorial Inheritance*
  • Myocardial Infarction* / epidemiology
  • Myocardial Infarction* / genetics
  • Myocardial Infarction* / psychology
  • Risk Assessment
  • Risk Factors
  • Risk Reduction Behavior