Performance of the Abbott RealTime and Roche Cobas TaqMan hepatitis C virus (HCV) assays for quantification of HCV genotypes

J Clin Microbiol. 2012 May;50(5):1769-72. doi: 10.1128/JCM.06723-11. Epub 2012 Feb 29.

Abstract

We evaluated the Abbott RealTime (ART) and Roche Cobas TaqMan Hepatitis C virus (HCV) viral load assays for quantification of HCV genotypes in patient specimens. The ART HCV assay was a more sensitive and precise tool for accurate HCV viral load quantification across the HCV genotypes tested, especially genotype 1b.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genotype
  • Hepacivirus / classification*
  • Hepacivirus / genetics
  • Hepacivirus / isolation & purification*
  • Hepatitis C / virology*
  • Humans
  • Molecular Diagnostic Techniques / methods*
  • Reagent Kits, Diagnostic*
  • Sensitivity and Specificity
  • Viral Load*

Substances

  • Reagent Kits, Diagnostic