Incidence of congenital toxoplasmosis in the City of Belém, State of Pará, Northern Brazil, determined by a neonatal screening program: preliminary results

Rev Soc Bras Med Trop. 2012 Feb;45(1):122-4. doi: 10.1590/s0037-86822012000100024.

Abstract

Introduction: The aim of this study was to determinate the incidence of congenital toxoplasmosis among a group of newborns (NBs) from Belém using neonatal screening.

Methods: Among the 6,000 newborns referred for investigation of genetic and metabolic diseases, 1,000 were selected for screening for congenital toxoplasmosis by determining the amount of IgM in the eluates of blood collected on filter paper. Positive tests were confirmed using paired serology of the NB and his mother.

Results: Out of the 1,000 NBs assessed, one had a positive screening result that was confirmed by paired serology.

Conclusions: The incidence of congenital toxoplasmosis in Belém was 10/10,000 live NBs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Protozoan / blood*
  • Brazil / epidemiology
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Incidence
  • Infant, Newborn
  • Neonatal Screening*
  • Toxoplasma / immunology*
  • Toxoplasmosis, Congenital / diagnosis
  • Toxoplasmosis, Congenital / epidemiology*

Substances

  • Antibodies, Protozoan
  • Immunoglobulin G
  • Immunoglobulin M