Magnetic enzyme nanogel (MENG): a universal synthetic route for biocatalysts

Chem Commun (Camb). 2012 Apr 4;48(27):3315-7. doi: 10.1039/c2cc30189j. Epub 2012 Feb 23.

Abstract

A universal synthetic route for magnetic enzyme nanogels (MENGs) was proposed, based on electrostatic interaction driven assembly and in situ polymerization from the surface of magnetic nanoparticles, to avoid chemical modification of proteins and hence structural and functional deterioration.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acrylic Resins / chemistry*
  • Armoracia / enzymology
  • Biocatalysis
  • Candida / enzymology
  • Cytochromes c / chemistry
  • Enzyme Stability
  • Enzymes, Immobilized / chemistry*
  • Gels
  • Horseradish Peroxidase / chemistry
  • Hydrogen-Ion Concentration
  • Kinetics
  • Lipase / chemistry
  • Magnetics
  • Microscopy, Electron, Transmission
  • Nanoparticles / chemistry*
  • Polymerization
  • Static Electricity
  • Surface Properties
  • Trypsin / chemistry

Substances

  • Acrylic Resins
  • Enzymes, Immobilized
  • Gels
  • polyacrylamide
  • Cytochromes c
  • Horseradish Peroxidase
  • Lipase
  • Trypsin