[Endoscopic management of luminal stenosis in inflammatory bowel disease]

Gastroenterol Hepatol. 2012 Jun-Jul;35(6):404-10. doi: 10.1016/j.gastrohep.2011.12.008. Epub 2012 Feb 16.
[Article in Spanish]

Abstract

Luminal stenosis is frequent in Crohn's disease (CD) due to transmural involvement. Before any endoscopic treatment, the presence of neoplastic stenosis should always be excluded. Endoscopic balloon dilatation has been used in several series to treat benign stenosis, mainly in CD with involvement of the distal ileon, colon or surgical anastomosis, with success rates of 51% to 85%, although recurrence is high. The concomitant use of injected steroids (triamcinolone) after endoscopic dilatation produces longer-lasting results, but there are few published reports. In patients with luminal stenosis refractory to conventional endoscopy, three emerging techniques may be useful: self-expanding metallic stents, biodegradable endoprostheses and intralesional infliximab injection.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Absorbable Implants
  • Anastomosis, Surgical
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use
  • Antibodies, Monoclonal / administration & dosage
  • Antibodies, Monoclonal / therapeutic use
  • Catheterization
  • Combined Modality Therapy
  • Constriction, Pathologic
  • Endoscopy, Gastrointestinal / methods*
  • Humans
  • Inflammatory Bowel Diseases / complications*
  • Inflammatory Bowel Diseases / drug therapy
  • Infliximab
  • Injections, Intralesional
  • Intestinal Obstruction / surgery
  • Intestinal Obstruction / therapy*
  • Stents
  • Triamcinolone / therapeutic use

Substances

  • Anti-Inflammatory Agents
  • Antibodies, Monoclonal
  • Triamcinolone
  • Infliximab