Bilateral thalamic infarct caused by spontaneous vertebral artery dissection in pre-eclampsia with HELLP syndrome: a previously unreported association

J Stroke Cerebrovasc Dis. 2012 Nov;21(8):914.e9-10. doi: 10.1016/j.jstrokecerebrovasdis.2012.01.007. Epub 2012 Feb 15.

Abstract

Cerebrovascular accidents are not rare during pregnancy and the postpartum period. Pre-eclampsia is a common condition that is characterized by proteinuria and de novo hypertension that may be complicated by hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome. Spontaneous cervical artery dissection has been rarely reported in the postpartum period but never in association with HELLP syndrome. We describe a case of pre-eclampsia and HELLP syndrome complicated in the postpartum period by bilateral thalamic infarct as result of left vertebral artery dissection. We speculated about the possible common etiopathologic mechanisms involved in this previously unreported association.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aspirin / therapeutic use
  • Cerebral Angiography / methods
  • Cerebral Infarction / diagnosis
  • Cerebral Infarction / drug therapy
  • Cerebral Infarction / etiology*
  • Female
  • HELLP Syndrome / diagnosis
  • HELLP Syndrome / etiology*
  • Humans
  • Postpartum Period
  • Pre-Eclampsia / diagnosis
  • Pre-Eclampsia / etiology*
  • Pregnancy
  • Risk Factors
  • Thalamus / blood supply*
  • Thalamus / diagnostic imaging
  • Tomography, X-Ray Computed
  • Vertebral Artery Dissection / diagnosis
  • Vertebral Artery Dissection / drug therapy
  • Vertebral Artery Dissection / etiology*

Substances

  • Aspirin