Attenuation of bone morphogenetic protein receptor type 2 expression in the pulmonary arteries of patients with failed Fontan circulation

J Thorac Cardiovasc Surg. 2012 Apr;143(4):e24-6. doi: 10.1016/j.jtcvs.2011.12.064. Epub 2012 Feb 15.

Authors

Hidekazu Ishida¹, Shigetoyo Kogaki, Kunihiko Takahashi, Keiichi Ozono

Affiliation

¹ Department of Pediatrics, Osaka University Graduate School of Medicine, Osaka, Japan.

PMID: 22341419
DOI: 10.1016/j.jtcvs.2011.12.064

No abstract available

MeSH terms

Adolescent
Autopsy
Bone Morphogenetic Protein Receptors, Type II / analysis*
Bone Morphogenetic Protein Receptors, Type II / genetics
Case-Control Studies
Child
Child, Preschool
Down-Regulation
Female
Fontan Procedure / mortality*
Heart Defects, Congenital / genetics
Heart Defects, Congenital / metabolism
Heart Defects, Congenital / mortality
Heart Defects, Congenital / pathology
Heart Defects, Congenital / surgery*
Humans
Immunohistochemistry
Japan
Male
Pulmonary Artery / chemistry*
Pulmonary Artery / pathology
RNA, Messenger / analysis
Real-Time Polymerase Chain Reaction
Treatment Failure

Substances

RNA, Messenger
BMPR2 protein, human
Bone Morphogenetic Protein Receptors, Type II