Three new monomeric indole alkaloids from the roots of Catharanthus roseus

J Asian Nat Prod Res. 2012;14(3):249-55. doi: 10.1080/10286020.2011.649728.

Abstract

Two new alkaloid glycosides (1 and 2) and a new monomeric indole alkaloid (3), together with 13 known ones (4-16), were isolated from the roots of Catharanthus roseus. The structures of new compounds were elucidated on the basis of the spectroscopic methods. The absolute configuration of compound 3 was established by the modified Mosher's method.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catharanthus / chemistry*
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Indole Alkaloids / chemistry
  • Indole Alkaloids / isolation & purification*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Roots / chemistry

Substances

  • 10-hydroxycathafoline 10-O-alpha-L-arabinopyranoside
  • 10-hydroxydeformodihydropseudoakuammigine-10-O-alpha-L-arabinopyranoside
  • 15(S)-hydroxy-14,15-dihydrovindolinine
  • Drugs, Chinese Herbal
  • Glycosides
  • Indole Alkaloids