Evaluation of bis-triphenylphosphano-copper(I)-butyrate (C3H7COOCu(PPh3)2) as catalyst for the synthesis of 1-glycopyranosyl-4-substituted-1,2,3-triazoles

Éva Bokor; Csenge Koppány; Zsombor Gonda; Zoltán Novák; László Somsák

doi:10.1016/j.carres.2012.01.004

Evaluation of bis-triphenylphosphano-copper(I)-butyrate (C3H7COOCu(PPh3)2) as catalyst for the synthesis of 1-glycopyranosyl-4-substituted-1,2,3-triazoles

Carbohydr Res. 2012 Apr 1:351:42-8. doi: 10.1016/j.carres.2012.01.004. Epub 2012 Jan 18.

Authors

Éva Bokor¹, Csenge Koppány, Zsombor Gonda, Zoltán Novák, László Somsák

Affiliation

¹ Department of Organic Chemistry, University of Debrecen, H-4010, P.O. Box 20, Debrecen, Hungary.

PMID: 22326108
DOI: 10.1016/j.carres.2012.01.004

Abstract

Bis-triphenylphosphano-copper(I)-butyrate (C(3)H(7)COOCu(PPh(3))(2)) was applied for the synthesis of O-peracylated 1-glycopyranosyl-4-substituted-1,2,3-triazoles from the corresponding glycosyl azides and alkynes. This catalyst proved superior to the CuSO(4)/L-ascorbic acid system even with sterically hindered and less reactive glycosyl azides.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Chemistry Techniques, Synthetic / methods*
Coordination Complexes / chemistry*
Triazoles / chemical synthesis*
Triazoles / chemistry*

Substances

Coordination Complexes
Triazoles