This paper describes an experimental study investigating pilots' manual flying skills. In today's line oriented flight training, basic flying skills are neglected frequently. So, the study examines the manual flying skills of commercial airline pilots under the influence of several performance shaping factors like training, practice or fatigue in a landing scenario. The landing phase shows a disproportionate high percentage of aircraft accidents and it is typically flown by hand. The study is to be undertaken with randomly selected pilots in a full motion flight simulator to ensure a high validity of the results.