Abstract
The organic germanium compound, Ge-132, has immune-modulating effects. We evaluated the symbiotic effects of Ge-132 with lactobacilli and oligosaccharide (LB/OS) on the immune responses of mice. The highest fecal IgA levels were observed in the mice receiving a low concentration of Ge-132 with LB/OS for 8 weeks. Our data suggest that LB/OS with a low concentration of Ge-132 stimulated the intestinal immunity.
MeSH terms
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Animals
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Drug Synergism
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Germanium / immunology*
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Germanium / pharmacology
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Immunity / drug effects*
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Immunoglobulin A / analysis
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Immunomodulation*
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Interferon Inducers
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Intestines / immunology
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Lactobacillus / immunology*
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Mice
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Oligosaccharides / immunology*
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Oligosaccharides / pharmacology
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Organometallic Compounds / immunology*
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Organometallic Compounds / pharmacology
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Propionates
Substances
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Immunoglobulin A
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Interferon Inducers
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Oligosaccharides
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Organometallic Compounds
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Propionates
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Germanium
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propagermanium