New insights into molecular players involved in neurotransmitter release

Physiology (Bethesda). 2012 Feb;27(1):15-24. doi: 10.1152/physiol.00035.2011.

Abstract

The strength of a synapse can profoundly influence network function. How this strength is set at the molecular level is a key question in neuroscience. Here, we review a simple model of neurotransmission that serves as a convenient framework to discuss recent studies on RIM and synaptotagmin.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • ATP-Binding Cassette Transporters / metabolism*
  • Animals
  • Models, Neurological*
  • Neurotransmitter Agents / metabolism*
  • Synapses / metabolism*
  • Synaptic Transmission / physiology*
  • Synaptotagmins / metabolism*

Substances

  • ATP-Binding Cassette Transporters
  • Neurotransmitter Agents
  • Synaptotagmins