Synthesis of O-spiro-C-aryl glycosides using organocatalysis

J Org Chem. 2012 Mar 2;77(5):2519-25. doi: 10.1021/jo202353r. Epub 2012 Feb 17.

Abstract

An organocatalysis strategy has been developed toward the synthesis of O-spiro-C-aryl glycosides with different configurations in the sugar part. This strategy has been extended to the synthesis of the Papulacandin class of compounds.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminoglycosides / chemical synthesis*
  • Aminoglycosides / chemistry
  • Catalysis
  • Echinocandins / chemical synthesis*
  • Echinocandins / chemistry
  • Models, Molecular
  • Molecular Structure
  • Organic Chemicals / chemistry*
  • Stereoisomerism

Substances

  • Aminoglycosides
  • Echinocandins
  • Organic Chemicals
  • papulacandins