The origin of the tRNA molecule: Independent data favor a specific model of its evolution

Massimo Di Giulio

doi:10.1016/j.biochi.2012.01.014

The origin of the tRNA molecule: Independent data favor a specific model of its evolution

Biochimie. 2012 Jul;94(7):1464-6. doi: 10.1016/j.biochi.2012.01.014. Epub 2012 Jan 28.

Author

Massimo Di Giulio¹

Affiliation

¹ Department of Philosophy and History of Science, Charles University, Viničná 7, CZ-128 44 Praha 2, Czech Republic. digiulio@igb.cnr.it

PMID: 22305822
DOI: 10.1016/j.biochi.2012.01.014

Abstract

The properties, historical and empirical observations of a model of the origin of the tRNA molecule are discussed. This model would predict that this molecule originated by means of the assembly of two hairpin-like structures of RNA. The conclusion is that the model possesses a relevant part of the truth on the origin of the tRNA molecule.

Publication types

Review

MeSH terms

Base Sequence
Evolution, Molecular*
Inverted Repeat Sequences
Models, Biological*
RNA, Transfer* / chemistry
RNA, Transfer* / genetics
RNA, Transfer* / metabolism

Substances

RNA, Transfer