Preliminary report of biological basis of sensitivity to the effects of cannabis on psychosis: AKT1 and DAT1 genotype modulates the effects of δ-9-tetrahydrocannabinol on midbrain and striatal function

Mol Psychiatry. 2012 Dec;17(12):1152-5. doi: 10.1038/mp.2011.187. Epub 2012 Jan 31.
No abstract available

Publication types

  • Controlled Clinical Trial
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Corpus Striatum / drug effects*
  • Dopamine Plasma Membrane Transport Proteins / genetics*
  • Dronabinol / pharmacology*
  • Genotype
  • Humans
  • Mesencephalon / drug effects*
  • Proto-Oncogene Proteins c-akt / genetics*
  • Psychoses, Substance-Induced / genetics*

Substances

  • Dopamine Plasma Membrane Transport Proteins
  • SLC6A3 protein, human
  • Dronabinol
  • AKT1 protein, human
  • Proto-Oncogene Proteins c-akt