Motion-insensitive optical coherence tomography based micro-angiography

Opt Express. 2011 Dec 19;19(27):26117-31. doi: 10.1364/OE.19.026117.

Abstract

An improved image processing procedure for suppressing the phase noise due to a motion artifact acquired during optical coherence tomography scanning and effectively illustrating the blood vessel distribution in a living tissue is demonstrated. This new processing procedure and the widely used procedure for micro-angiography application are based on the selection of high-frequency components in the spatial-frequency spectrum of B-mode scanning (x-space), which are contributed from the image portions of moving objects. However, by switching the processing order between the x-space and k-space, the new processing procedure shows the superior function of effectively suppressing the phase noise due to a motion artifact. After the blood vessel positions are precisely acquired based on the new processing procedure, the projected blood flow speed can be more accurately calibrated based on a previously reported method. The demonstrated new procedure is useful for clinical micro-angiography application, in which a stepping motor of generating motion artifacts is usually used in the scanning probe.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Angiography / instrumentation*
  • Artifacts*
  • Equipment Design
  • Equipment Failure Analysis
  • Image Enhancement / instrumentation*
  • Miniaturization
  • Motion
  • Tomography, Optical Coherence / instrumentation*