Differential sensitivity of RIP3-proficient and deficient murine fibroblasts to camptothecin anticancer drugs

Acta Pharmacol Sin. 2012 Mar;33(3):426-8. doi: 10.1038/aps.2012.1. Epub 2012 Jan 23.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Apoptosis / drug effects
  • Apoptosis / genetics
  • Camptothecin / pharmacology*
  • Fibroblasts / drug effects*
  • Fibroblasts / enzymology
  • Fibroblasts / metabolism
  • Fibroblasts / pathology
  • Mice
  • NIH 3T3 Cells
  • Necrosis
  • Receptor-Interacting Protein Serine-Threonine Kinases / genetics*
  • Receptor-Interacting Protein Serine-Threonine Kinases / metabolism*

Substances

  • Antineoplastic Agents
  • Receptor-Interacting Protein Serine-Threonine Kinases
  • Ripk3 protein, mouse
  • Camptothecin