[Sesquiterpenoids from the whole plant of Sarcandra glabra]

Xiong Li; Yu-feng Zhang; Liu Yang; Yi Feng; Yi-ming Liu; Xing Zeng

[Sesquiterpenoids from the whole plant of Sarcandra glabra]

Yao Xue Xue Bao. 2011 Nov;46(11):1349-51.

[Article in Chinese]

Authors

Xiong Li¹, Yu-feng Zhang, Liu Yang, Yi Feng, Yi-ming Liu, Xing Zeng

Affiliation

¹ Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, China.

PMID: 22260027

Abstract

To study the sesquiterpenoid constituents in the whole plant of Sarcandra glabra, silical column chromatography, Sephadex LH-20, reverse phase ODS column chromatography and preparative HPLC were used to isolate 70% EtOH extract of Sarcandra glabra. The structures were elucidated based on spectroscopic data (HR-ESI-MS, 1H NMR, 13C NMR, HSQC, HMBC and NOESY). Four sesquiterpenoids were obtained and identified as 4alpha-hydroxy-5alphaH-lindan-8 (9)-en-8, 12-olide (1), chloranthalactone E (2), 8beta, 9alpha-dihydroxylindan-(5), 7 (1)-ieb-8alpha, 12-olide (3) and chloranoside A (4), respectively. Compound 1 is a new sesquiterpene lacone.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Magnoliopsida / chemistry*
Molecular Structure
Plants, Medicinal / chemistry*
Sesquiterpenes / chemistry
Sesquiterpenes / isolation & purification*

Substances

4alpha-hydroxy-5alphaH-lindan-8(9)-en-8,12-olide
Sesquiterpenes