Pandemic influenza A (H1N1) (pH1N1) was first identified in North America in early 2009. The pandemic flu outbreak during the 2009–2010 influenza season demonstrated how rapidly a new strain of flu can emerge and spread. Vaccination is the most effective method to prevent influenza, and vaccination during a pandemic is critical in limiting morbidity and mortality. Unfortunately, reports of vaccination rates for pH1N1 vaccines during the 2009–2010 influenza season indicated low rates for various demographic groups, including pregnant women, health care workers, child care workers, college students, and the general public. Furthermore, when asked about perceptions of pH1N1 vaccines, respondents in a variety of studies from the pH1N1 pandemic indicated common and universal misconceptions about influenza vaccines, especially in regard to perceptions of need, efficacy and safety. Therefore, if vaccination rates are to increase, an important outcome especially during pandemics, the psychological characteristics underpinning perceptions of influenza vaccines need to be understood better.