Synthesis of indolo [1,2-a]quinoxalines via a Pd-catalyzed regioselective C-H olefination/cyclization sequence

Org Lett. 2012 Feb 3;14(3):740-3. doi: 10.1021/ol203275b. Epub 2012 Jan 18.

Abstract

A highly efficient approach to indolo [1,2-a]quinoxaline derivatives through a Pd-catalyzed regioselective C-H olefination/cyclization sequence has been developed. This transformation has a wide range of substrates with various functional groups, and the corresponding heterocyclic products were obtained in good yields.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemistry*
  • Catalysis
  • Cyclization
  • Indoles / chemistry*
  • Models, Molecular
  • Molecular Structure
  • Palladium / chemistry*
  • Quinoxalines / chemistry*
  • Stereoisomerism

Substances

  • Alkenes
  • Indoles
  • Quinoxalines
  • Palladium